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Updated: Jun 27, 2025

Induction and Assessment of Levodopa-induced Dyskinesias in a Rat Model of Parkinson's Disease
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如何PBPK可以帮助理解老药物,并告知老年人的剂量:阿曼塔丁病例研究

Olha Shuklinova1,2, Sibylle Neuhoff2, Sebastian Polak2,3

  • 1Doctoral School of Medical and Health Sciences, Jagiellonian University Medical College, Kraków, Poland.

Clinical pharmacology and therapeutics
|April 26, 2024
PubMed
概括

这项研究模拟了老年人群中阿曼塔丁的药理动力学,揭示了脏输送活性下降. 这种理解对于在老年人和特殊人群中安全使用阿曼塔丁剂量至关重要.

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