激发性/抑制性运动平衡反映了联合行动协调期间的个体差异
Enrico Vescovo1,2, Pasquale Cardellicchio2,3, Alice Tomassini1
1Center for Translational Neurophysiology of Speech and Communication, Istituto Italiano di Tecnologia, Ferrara, Italy.
The European journal of neuroscience
|April 26, 2024
概括
了解联合行动协调需要平衡内部预测与实时合作伙伴线索. 这项研究揭示了在联合行动中早期 (预测性) 和晚期 (反应性) 运动控制策略的独特神经特征.
科学领域:
- 神经科学是一个神经科学.
- 发动机控制器的控制器
- 人与计算机的交互
背景情况:
- 联合行动 (JA) 涉及连续的运动共同调节,整合了来自合作伙伴的自上而下的上下文和自下而上的动态线索.
- 感官运动回路的激发抑制平衡对于JA的动态动作选择和执行至关重要.
- 在处理自上而下和自下而上信息的个体差异影响了JA协调.
研究的目的:
- 通过检查皮质脊髓刺激 (CSE) 和抑制来研究联合行动 (JA) 协调的神经生理基础.
- 探索如何先前的知识 (自上而下) 和在线运动线索 (自下而上) 在JA期间调节传感运动处理.
- 描述与在JA期间采用的不同行为策略相关的神经特征.
主要方法:
- 设计了一个单手JA任务,参与者拿着瓶子,而盟友伸手去拿.
- 对目标瓶子的先前知识被操纵 (已知与未知).
- 在线跨磁刺激 (TMS) 在关键行动点测量了皮质脊髓刺激性 (CSE) 和皮质静止期 (cSP).
主要成果:
- 随着先前信息的可用性,CSE调制很早就发生了,反映了自上而下的处理.
- cSP调制发生在行动期间的晚些时候,独立于先前的知识,这表明了自下而上的暗示集成.
- 独特的激发/抑制特征标志着有利于早期与晚期力量施加的策略,影响协调和代谢成本.
结论:
- CSE和cSP调制的相互作用反映了JA中的上下文前置和在线动态线索的动态集成.
- 在JA中选择行为策略与与激发-抑制平衡相关的特定神经生理学特征有关.
- 了解激发-抑制平衡为确定JA协调中的个体差异提供了神经生理学基础.
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