胎儿大动脉膜整形作为复杂的治疗策略的第一步
Sofía Grinenco1, Horacio Antonio Aiello2, César Hernán Meller2
1Pediatric Cardiology Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano, Buenos Aires, Argentina.
Prenatal diagnosis
|April 26, 2024
概括
胎儿大动脉膜整形 (FAV) 在治疗关键大动脉狭窄症方面显示出有前途,以预防低可塑性左心综合征. 虽然具有挑战性,但FAV是可行的,并且可以导致幸存者的双心室循环.
科学领域:
- 心血管外科心血管外科
- 胎儿医学 胎儿医学
- 儿童心脏病学 儿童心脏病学
背景情况:
- 胎儿的关键性大动脉狭窄可以导致低可塑性左心综合征.
- 胎儿大动脉膜整形 (FAV) 是一种建议的干预措施,以解决这种情况.
- FAV旨在预防子宫内严重的左心发育不良.
研究的目的:
- 评估胎儿大动脉膜整形术 (FAV) 的可行性和结果.
- 评估FAV作为一个复杂的治疗策略的初步步骤,用于胎儿关键大动脉狭窄.
- 报告一系列接受FAV.患者的长期结果.
主要方法:
- 在18年的时间里,对接受FAV的患者进行了回顾性审查.
- 分析技术成功率,周围手术的胎儿死亡,以及对后续的损失.
- 评估出生时的左心室 (LV) 尺寸以及随后的心脏干预和结果.
主要成果:
- 在26个胎儿的27个FAV手术中的82%取得了技术上的成功.
- 围绕手术的胎儿死亡发生在22%,在后半部分的队列下降到15%.
- 在幸存者中,46%的出生时具有正常大小的LV,其中5/6在28天内实现了双心室循环.
结论:
- 胎儿大动脉膜整形 (FAV) 是可行的,没有母亲的并发症.
- 大约40%的幸存者在28天内实现了双心室循环.
- 产后干预措施是多样化的,突出了FAV之后心血管治疗的创新性质.
相关概念视频
Mitral Stenosis III: Medical Management
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
Aortic Regurgitation III: Medical Management
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
Aneurysm III: Interprofessional Care
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...


