关于抗生素耐药细菌在水生生态系统中殖民塑料垃圾的新兴问题
Ifra Ferheen1, Roberto Spurio1, Stefania Marcheggiani2
1School of Biosciences and Veterinary Medicine, University of Camerino, 62032 Camerino, Italy.
Antibiotics (Basel, Switzerland)
|April 26, 2024
概括
水中的塑料碎片含有抗生素耐药细菌 (ARB) 和它们的基因. 这项研究在塑料上发现了常见的人类病原体,所有塑料都表现出高抗生素耐药性,造成环境和健康风险.
科学领域:
- 环境微生物学环境微生物学
- 公共卫生 公共卫生
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 水生环境中的塑料基板可以容纳致病细菌.
- 抗生素耐药细菌 (ARB) 对环境和人类健康构成重大威胁.
- 了解ARB及其抗生素耐药基因 (ARG) 在塑料上的患病率至关重要.
研究的目的:
- 为了检查是否存在Staphylococcus spp. 的存在. 和Klebsiella spp. 这种疾病. 在内陆水体中的塑料基板上.
- 在这些细菌分离物中识别抗生素耐药性概况和ARG.
- 评估与塑料相关的ARB相关的潜在健康风险.
主要方法:
- 使用选择性和染色基媒体进行微生物学分析.
- 生物化学和分子鉴定 (16S rDNA测序,BLAST分析).
- 抗生素敏感性测试 (Kirby-Bauer盘扩散) 和基因型ARG分析.
主要成果:
- 克莱布西埃拉 spp. 的种类. 已经得到证实. 葡萄球菌 spp. 葡萄球菌 spp. 它们被确定为lysinibacillus spp. (63.6%) 和Exiguobacterium acetyllicum (36.3%). 这两种类型的细菌是最常见的.
- 所有分离的细菌都对九种经过测试的抗生素有很高的耐药性.
- 检测到1类整体基因和18个ARG,这表明具有显著的抗性负担.
结论:
- 塑料碎片充当了具有广泛抗生素耐药性的机会性人类病原体的储存库.
- 水中塑料污染有助于ARB和ARG的传播.
- 这凸显了塑料垃圾对环境和人类健康的新兴风险.
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