初级动脉高血压与年轻成年人认知功能障碍相关:跨部分受控研究的结果
Kristijonas Puteikis1,2, Karolis Ažukaitis1,2, Danguolė Dadurkevičienė2
1Faculty of Medicine, Vilnius University, 03101 Vilnius, Lithuania.
Behavioral sciences (Basel, Switzerland)
|April 26, 2024
概括
患有初级高血压 (PH) 的年轻人表现出反应速度和持续注意力的认知缺陷. 这些差异与体重指数 (BMI) 有关,但高血压独立预测了注意力问题.
科学领域:
- 神经科学是一个神经科学.
- 心血管医学 心血管医学
- 心理学 心理学 心理学
背景情况:
- 在不同年龄组的初级高血压 (PH) 中记录了认知功能障碍,但对年轻成年人的数据有限.
- 了解成年早期的认知影响对于长期的健康管理至关重要.
研究的目的:
- 调查PH和健康对照的年轻成年人之间的认知表现差异.
- 确定在成年早期受PH影响的特定认知领域.
主要方法:
- 横截面研究,将PH的年轻成年人 (18-45岁) 与匹配的健康对照进行比较.
- 神经心理学评估包括测试口语流,记忆,反应速度,注意力和执行功能.
- 统计分析包括t测试,曼·惠特尼U测试,ANCOVA和回归模型,并对BMI进行调整.
主要成果:
- 患有PH的参与者表现出反应时间和持续注意力任务的表现较差.
- 这些群体差异在调整BMI后并不显著.
- 高办公室缩血压 (oSBP) 独立地与持续注意力较差有关.
结论:
- 患有PH的年轻人表现出反应速度受损和持续的注意力.
- 虽然BMI混了一些认知差异,但高的oSBP直接影响了持续的注意力.
- 需要进行更大规模的试验来确认与年轻成年人PH相关的特定认知特征.
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