相关实验视频
Updated: Jun 27, 2025
13:45
Merkel Cell Polyomavirus Infection and Detection
Published on: February 7, 2019
9.9K
默克尔细胞癌重叠波恩病:两例病例报告和文献综述
Xueqin Chen1, Xiao Song1, Hui Huang1
1Department of Dermatology, Southwest Hospital, Army Medical University, No. 30, Gaotanyan Street, Shapingba District, Chongqing, 400038, China.
Journal of cancer research and clinical oncology
|April 26, 2024
概括
默克尔细胞癌 (MCC) 叠加波恩病 (BD) 是一种罕见的皮肤癌,主要影响老年妇女的脸部. 由于复发和转移率高,早期检测和管理至关重要.
科学领域:
- 皮肤病学 皮肤病学
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 默克尔细胞癌 (MCC) 是一种罕见的,激进的皮肤癌.
- 恩病 (BD) 是一种状细胞癌 in situ 的形式.
- 覆盖MCC的BD是一种异常罕见的亚型,管理不清楚.
研究的目的:
- 要总结流行病学,临床特征,转移,复发和MCC重叠BD的管理.
- 介绍两个新的病例,并回顾过去11年的文献.
主要方法:
- 在PubMed,ResearchGate和Google Scholar的文献搜索中使用关键字:"默克尔细胞癌"和"恩病".
- 对2013年1月至2023年12月期间诊断的13例病例 (包括2例新病例) 的回顾性分析.
- 组织病理学和免疫组织化学确认.
主要成果:
- 分析了13例病例,主要是老年女性 (>70岁),病变主要在脸上.
- 病变出现在红色/深棕色斑点上的坚固,深红色结节或孤立的结节.
- 扩展局部切除是主要的治疗方法,但局部复发很常见;4例发生转移. 一名患者对转移性疾病的阿维卢马布反应良好.
结论:
- MCC重叠的BD很少见,经常被误诊,并且具有很高的复发率,特别是在脸上.
- 诊断时的晚期疾病表明预后不佳;早期检测至关重要.
- AEIOUN缩写词可能有助于临床识别;需要提高意识和管理策略.
更多相关视频
09:37Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
2.3K
09:52Detection and Isolation of Circulating Melanoma Cells using Photoacoustic Flowmetry
Published on: November 25, 2011
15.9K
相关概念视频
01:30Skin Cancer
4.1K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.1K
02:50Combination Therapies and Personalized Medicine
4.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.9K