社区贫困是否影响腰部疼痛和关节炎:使用多层双胞胎设计的经验研究
Yingyu Feng1, Jocelyn L Bowden1, David J Hunter1
1Sydney Musculoskeletal Health, The Kolling Institute, The University of Sydney and Rheumatology Department, Royal North Shore Hospital, Sydney, Australia.
PloS one
|April 26, 2024
概括
在这项双胞胎研究中,社区贫困没有显示出与腰部疼痛 (LBP) 或关节炎的联系. 个人教育水平,而不是邻居因素,与LBP风险有关.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 健康的社会经济决定因素
背景情况:
- 社区贫困与各种健康问题有关,但其对腰部疼痛 (LBP) 和关节炎的影响尚不清楚.
- 了解这些关联对于公共卫生干预和有针对性的支持至关重要.
研究的目的:
- 调查邻里贫困和LBP/关节炎之间的关联.
- 在这些条件下,探索社区贫困和个人社会经济地位 (SES) 之间的相互作用.
主要方法:
- 利用单胞胎 (MZ) 双胞胎的数据来控制遗传和共同的环境因素.
- 采用多层模型来分析邻里贫困和个人SES与LBP/关节炎相关,以BMI和农村等共变量进行调整.
主要成果:
- 在邻里贫困和LBP (P=0.26) 或关节炎 (P=0.61) 之间没有发现显著的关联.
- 与拥有学士学位的人相比,没有学士学位的人报告LBP (OR 1.44) 和LBP/关节炎组合 (OR 1.67) 的几率更高.
- 家庭收入与腰痛或关节炎没有显著的关联.
结论:
- 这项研究发现,邻里贫困与腰痛或关节炎的患病率之间没有显著的联系.
- 建议使用多级建模进行进一步的研究,以探索邻里对LBP和关节炎的影响.
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