"从新陈代谢到新陈代谢":关于B族维生素相互作用,生物强化和缺陷的整体考虑
Lisa De Zanetti1, Dominique Van Der Straeten1
1Laboratory of Functional Plant Biology, Ghent University, K.L. Ledeganckstraat 35, B-9000 Ghent, Belgium.
Current opinion in biotechnology
|April 26, 2024
概括
微量营养素营养不良正在增加,原因是食物质量下降和饮食变化. 生物强化超越传统方法的多样化,比如使用B族维生素的代谢工程,对全球健康至关重要.
科学领域:
- 农业科学 农业科学
- 营养科学 营养科学
- 生物技术是生物技术.
背景情况:
- 全球饮食转变,包括植物性饮食和气候变化影响,正在降低营养价值,增加B族维生素缺乏.
- 目前的生物强化工作主要针对维生素A,铁和,忽视了其他必需的微量营养素.
- 微量营养素营养不良影响低收入和高收入人口,需要更广泛的干预策略.
研究的目的:
- 强调迫切需要多样化的生物强化战略,以解决广泛存在的维生素B缺乏症.
- 提出代谢工程作为一种关键的生物技术方法,以提高作物中的B族维生素含量.
- 倡导全面的"代谢到代谢"战略,包括作物和整个食物链.
主要方法:
- 审查农业,饮食和气候变化的当前趋势,影响营养价值.
- 分析微量营养素生物强化常规育种的局限性.
- 探索代谢工程和生物技术工具的潜力,以提高植物中的B维生素水平.
主要成果:
- 饮食下降和特定的饮食趋势与全球增加的维生素B缺乏症有关.
- 传统的生物强化范围有限,需要先进的技术.
- 代谢工程为增强多种B族维生素提供了一条可行的途径,取决于科学和监管进步.
结论:
- 需要在食物链中转向质量而不是数量的范式转变.
- 整合"代谢与代谢"的方法和生物技术创新对于有效的生物强化至关重要.
- 持续的研究,技术进步和公共资金对于通过生物强化对抗微量营养素营养不良至关重要.
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