极端动物对远紫外线光的敏感性,以减少太空飞船组装设施中的生物负担
Camryn Petersen1, Manuela Buonanno1, Lisa Guan2
1Center for Radiological Research, Columbia University Irving Medical Center, New York, NY, United States.
Life sciences in space research
|April 26, 2024
概括
远紫外线光有效地减少了与行星保护相关的微生物污染. 这种杀菌光为航天器组装设施提供了一种安全的替代方案,可以使各种细菌物种和子失活.
科学领域:
- 微生物学 微生物学
- 太空科学 太空科学
- 公共卫生 公共卫生
背景情况:
- 保护地球需要严格的微生物控制,以防止生物污染.
- 传统的紫外线消毒方法存在健康风险,限制了它们在被占用地区的使用.
- 远紫外线 (200-230纳米) 光是一种新兴技术,有可能安全减少微生物.
研究的目的:
- 研究222纳米远紫外线光对灭活行星保护相关微生物的有效性.
- 评估细菌植物细胞和子对远紫外线辐射的敏感性.
- 评估远紫外线作为航天器组装的安全有效的脱污方法.
主要方法:
- 细菌植物细胞和子暴露在222nm远紫外线光线下.
- 使用生存试验量化微生物无活化的量化.
- 对抗性模式的分析,包括确定日志减小剂量和D90值.
主要成果:
- 所有测试的植物性细菌细胞都对222nm远紫外线敏感,具有不同程度的耐药性.
- 在植物细胞中,Deinococcus radiodurans表现出最高的耐药性,需要112mJ/cm2才能减少1个日志.
- 在测试过的子中,菌胞是最耐药的,其D90值为6.8mJ/cm2.
结论:
- 222nm远紫外线光是有效的减少微生物生物负担相关的行星保护.
- 远紫外线为太空飞船组装提供了一个有希望的,低危险的替代方案,而不是传统的紫外线消毒.
- 这项技术可以通过改善微生物控制来提高太空探索任务的安全性和成功.
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