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相关概念视频

Higher Mental Functions of the Brain: Language01:10

Higher Mental Functions of the Brain: Language

Language is a system of communication that allows the expression of thoughts, ideas, and feelings. The brain processes language in both hemispheres.
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...

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Association between motor cortex grey matter loss and inability to control an ECoG-based implanted Brain-Computer Interface in ALS.

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Stable speech BCI performance during slow progression of ALS: A longitudinal ECoG study.

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相关实验视频

Updated: Jul 2, 2026

A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis ALS
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在线语音合成使用长期植入的脑电脑接口在一个ALS个体.

Miguel Angrick1, Shiyu Luo2, Qinwan Rabbani3

  • 1Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. mangric1@jhu.edu.

Scientific reports
|April 26, 2024
PubMed
概括

这项研究展示了一个脑-计算机接口 (BCI),为患有ALS的人合成可理解的语言. BCI成功地从大脑活动中重建了口语,提供了新的沟通途径.

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科学领域:

  • 神经科学是一个神经科学.
  • 生物医学工程 生物医学工程
  • 语音合成 语音合成

背景情况:

  • 像ALS这样的神经系统疾病会严重损害语言.
  • 现有的沟通辅助工具可能无法完全恢复自然语言.
  • 大脑-计算机接口 (BCI) 提供了恢复通信的潜力.

研究的目的:

  • 开发和评估在线语音合成BCI,用于发音障碍者.
  • 评估来自电皮质谱 (ECoG) 信号的合成语音的可理解性和可靠性.
  • 探索使用循环神经网络来解码语音意图.

主要方法:

  • 在患有ALS的参与者身上使用了长期植入的BCI与电皮质谱 (ECoG).
  • 采用三级循环神经网络方法来识别,解码和合成语音.
  • 用6个关键词的词汇来测试BCI,用于控制通信板.

主要成果:

  • 成功演示了参与者选择的可理解单词的在线合成.
  • 通过人类听众实现了80%的单词识别准确度,用于合成语音.
  • 展示了ECoG信号对基于语音的BCI的可靠性和稳定性.

结论:

  • 长期植入的BCI可以使ALS患者产生合成语音.
  • 开发的BCI保留了参与者的语音配置文件.
  • 这项技术对恢复言语丧失患者的沟通充满希望.