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Updated: Jun 27, 2025

Evaluating Regional Pulmonary Deposition using Patient-Specific 3D Printed Lung Models
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吸入利 propionate 和沙米特醇新酸盐的药用动力学模型,以量化批量对批量的变化

Shuhui Li1, Kairui Feng2, Jieon Lee2

  • 1Center for Translational Medicine, School of Pharmacy, University of Maryland, 20 North Pine Street, Baltimore, Maryland, 21201, USA.

The AAPS journal
|April 26, 2024
PubMed
概括

在Advair Diskus (酸/沙米特醇氨基酸) 中的批量变异性会影响仿制药开发. 为了解决这一问题,制造了药理动力学模型,揭示了细颗粒物分数与药物暴露相关,有助于未来的生物等价性研究.

关键词:
在Advair Diskus上进行讨论.从一个批次到另一个批次的可变性.这种药物是fluticasone.人口 PK 人口 PK盐度测量仪 (salmeterol) 是一种

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