电化学驱动的微电极用于最小侵入性的外围神经接口
Chaoqun Dong1, Alejandro Carnicer-Lombarte1, Filippo Bonafè1,2
1Electrical Engineering Division, Department of Engineering, University of Cambridge, Cambridge, UK.
Nature materials
|April 26, 2024
概括
新的柔软机器人神经手提供了一种无,最少侵入性的方式与外围神经进行接口. 这项技术使可靠的生物电子连接能够用于诊断和治疗神经系统疾病.
科学领域:
- 生物医学工程 生物医学工程
- 神经技术的神经技术
- 材料科学 材料科学 材料科学
背景情况:
- 外围神经电极阵列对于神经疾病的诊断和治疗至关重要.
- 目前的方法涉及复杂的手术,具有很高的神经损伤风险.
研究的目的:
- 使用软机器人执行器和灵活的电子设备开发高度可调整的神经袖口.
- 为外围神经创建一个最小的侵入性,无接口.
主要方法:
- 电化学驱动的导电聚合物软执行器与低阻抗微电极的集成.
- 开发了通过低电压 (数百毫伏) 激活的自闭神经袖口.
- 在体内验证使用老鼠坐骨神经模型.
主要成果:
- 神经袖子表现出积极抓住和包裹周围的微妙的神经.
- 成功形成和维护一个自闭,可靠的生物电子接口,没有或粘合剂.
- 该技术在老鼠模型中的体内验证.
结论:
- 这种柔软的电化学执行器和神经技术的新整合,为最小侵入性外科手术程序提供了一条道路.
- 开发的神经手套提供了高质量的生物电子接口,以改善神经监测和治疗.
- 无的方法可以降低植入过程中神经损伤的风险.
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