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孕妇妊娠糖尿病婴儿的口腔微生物群:一个系统的审查

Nicole Camoni^1,2, Giulio Conti³, Alessandra Majorana⁴

¹ASST Valle Olona, Dental Unit, 21052 Gallarate, Italy.

Children (Basel, Switzerland)

|April 27, 2024

概括

孕期糖尿病 (GDM) 的母亲产生的婴儿的口腔微生物群可能与没有GDM的婴儿不同. 然而,目前的证据有限,需要进一步调查,因为研究偏差很高.

科学领域:

微生物学微生物学
产科产科产科产科产科
新生儿健康新生儿健康

背景情况:

孕期糖尿病 (GDM) 影响5-20%的怀孕.
GDM与不良妊娠结果有关.
母亲GDM对婴儿口腔微生物群的影响正在调查中.

研究的目的:

审查和分析有关GDM母亲及其婴儿口腔微生物群组成的研究.
为了比较GDM受影响和未受影响的母婴对之间的口腔微生物群.

主要方法:

在PubMed,Embase,Scopus和Google Scholar的系统文献搜索.
对12项选定的研究进行了定性分析.
使用乔安娜·布里格斯研究所工具进行偏见风险评估.

主要成果:

在八项研究中,六项研究发现GDM和非GDM组之间的母体口腔微生物群有显著差异.
四项研究表明婴儿口腔微生物群的变化,包括GDM组中的枯竭的Firmicutes和富含蛋白质菌.
所有纳入的研究都呈现出高偏差风险.

结论:

婴儿口腔微生物群在母亲GDM的背景下可能有所不同.
目前没有足够的证据来证实这些差异,因为现有研究中的偏差风险很高.
需要进一步进行高质量的研究,以阐明母亲GDM和婴儿口腔微生物组之间的关系.

关键词:

孕期糖尿病孕期糖尿病我们的微生物群.新生儿的微生物群口腔中的微生物群.

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