关于夜间婴儿哭泣评估 (NICE) 和反流性疾病 (RED) 的研究
Greta Carabelli1, Ivan Binotto1, Chiara Armano1
1Pediatric Department, "F. Del Ponte" Hospital, University of Insubria, 21100 Varese, Italy.
Children (Basel, Switzerland)
|April 27, 2024
概括
对婴儿哭泣的经验性酸抑制治疗没有证据支持. 胃食道逆流 (GER) 不总是适用于婴儿无法解释的持续哭泣,即使有夜间症状.
科学领域:
- 儿科 儿科 儿科
- 胃肠病学 胃肠病学
- 婴儿健康 婴儿健康
背景情况:
- 夜间的婴儿哭泣经常用抑制酸的药物来控制.
- 这项研究调查了患有无法解释的持续哭泣的婴儿胃食道逆流 (GER) 的患病率和特征.
研究的目的:
- 评估婴儿GER的患病率和特征,这些婴儿有不明原因的持续哭泣.
- 为了确定在这种情况下是否有必要进行经验性抑制酸的治疗.
主要方法:
- 消化管阻抗-pH监测 (MII-pH) 用于婴儿 (0-12个月) 无法解释的持续哭泣.
- 排除标准包括胃肠道形,神经功能障碍和感染.
- 分析的数据包括GER症状,I-GERQ-R得分和MII-pH结果.
主要成果:
- 60%的持续哭泣的婴儿有正常的MII-pH检测结果.
- 52%的婴儿在夜间哭泣,其中54%的婴儿MII-pH正常.
- 无论是I-GERQ-R得分还是反频率都没有预测异常的MII-pH结果.
结论:
- 不建议用酸抑制剂实证治疗持续无法解释的哭泣的婴儿.
- GER并非始终被确定为无法解释的持续性或夜间婴儿哭泣的原因.
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