在一个单一中心连续一系列的多水的氨缩:说明,风险和围产期结果
Arianna Laoreti1,2, Valentina Sala2, Daniela Casati1,2
1Fetal Therapy Unit "U. Nicolini", Buzzi Children's Hospital, University of Milan, 20154 Milan, Italy.
Children (Basel, Switzerland)
|April 27, 2024
概括
对于严重的多水瘤而言,氨膜切除是缓解母亲症状的安全程序. 这种在三级中心进行的干预与高胎儿异常率有关,但很少出现并发症.
科学领域:
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 周围生理学 周围生理学
- 产科 产科 产科 产科 产科
背景情况:
- 严重的多水症往往表明潜在的胎儿异常.
- 症状多水症可能会显著影响母亲的幸福感.
- 氨缩减是一种潜在的干预措施,用于管理母亲的症状.
研究的目的:
- 为了评估氨缩减的安全性和结果,用于症状多水.
- 为了分析怀孕和新生儿后的结局amnioreduction.
- 为了确定胎儿异常的发病率,在怀孕经历了羊膜缩小.
主要方法:
- 对86例怀孕 (单胎和双胎) 进行了回顾性研究,这些怀孕因症状多水症而经历了羊膜缩小 (2010-2023年).
- 从医疗记录,出院报告和电话召回中收集的数据.
- 分析包括指示,手术技术和母婴结局.
主要成果:
- 胎儿异常存在于79%的病例中,主要是胃肠道阻塞异常.
- 第一次羊膜切除时的中位妊娠年龄为32.5周.
- 术后并发症很少见;产生的妊娠年龄中位数为36.5周.
- 怀孕延长了手术后30天的中位数.
- 过早分娩 (<37周) 发生在48.8%,其中26.7%在34周前分娩.
- 在23.2%的患者中,发生过早的膜破裂 (<36周).
结论:
- 膜切除是一种相当安全的程序,用于缓解与严重多水症相关的孕产妇症状.
- 这些高风险怀孕需要在第三级推中心进行管理,因为需要多学科护理.
- 该程序与低并发症率有关,尽管胎儿异常的发病率很高.
相关概念视频
Teratogenicity
2.4K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.4K
Local Anesthetics: Clinical Application as Epidural Anesthesia
429
Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
429


