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Updated: Jun 27, 2025

Protocol for the Differentiation of Human Induced Pluripotent Stem Cells into Mixed Cultures of Neurons and Glia for Neurotoxicity Testing
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谷氨诱导Keap1 S-谷氨基化并通过激活Nrf2缓解振荡性葡萄糖诱导的β细胞功能障碍

Xiufang Chen1, Qian Zhou1, Huamin Chen1

  • 1Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou 325035, China.

Antioxidants (Basel, Switzerland)
|April 27, 2024
PubMed
概括

谷氨酸 (GSH) 通过激活Nrf2通路来防止由葡萄糖诱导的振荡性胰腺β细胞衰竭. 这种抗氧化剂增强了Keap1的S-氨基化,促进了Nrf2核转位,恢复了β细胞的功能.

关键词:
凯普1号码是什么意思Nrf2 没有任何问题.在S-Glutathionylation的过程中,葡萄糖毒性 葡萄糖毒性葡萄糖氨酸氨酸是什么?在糖尿病前期,糖尿病前期.的β细胞.

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