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Updated: Jun 27, 2025

Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines
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新型1,5-二甲酸衍生物的双重抗炎和抗癌活性:分子建模,合成,体外活性和动力学研究研究

Priya Deivasigamani1, S M Esther Rubavathy2, Narayanan Jayasankar3

  • 1Dr APJ Abdul Kalam Research Lab, Department of Pharmaceutical Chemistry, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur 603203, Chengalpattu District, Tamil Nadu, India.

Biomedicines
|April 27, 2024
PubMed
概括

新的皮拉衍生物被设计和合成以向COX-2抑制和癌症. 化合物T3和T5显示出强大的COX-2抑制,T5显示出更高的选择性和结合亲和力,表明其作为抗癌剂的潜力.

关键词:
1,5-迪阿里尔皮拉醇是一种这是一种COX酶.这是一种抗炎药物.这是一种抗癌药物.

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