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Updated: Jun 27, 2025

Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates
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T细胞参与者-结构和功能原理以及在血液恶性瘤中的应用

Paweł Cech1, Katarzyna Skórka1, Laura Dziki1

  • 1Department of Experimental Hematooncology, Medical University of Lublin, 20-093 Lublin, Poland.

Cancers
|April 27, 2024
PubMed
概括

双特异性抗体 (BsAbs),称为T细胞参与剂 (TCEs),通过引导免疫T细胞向癌细胞,彻底改变了血液癌症治疗. 目前正在进行的研究旨在克服局限性并扩大TCE治疗以获得更好的患者结果.

关键词:
参与T细胞参与者 (TCE)使用T细胞参与治疗的疗法.两种特异性T细胞吸引剂 (BiTE)两种特异性抗体 (BsAb) 的抗体这就是Blinatumomabomab.血液学中的免疫疗法.

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