老年人患有不安腿综合征或威利斯-埃克博姆病的长度认知轨迹
Ioannis Liampas1, Vasileios Siokas1, Andreas Kyrozis2
1Department of Neurology, University Hospital of Larissa, School of Medicine, University of Thessaly, 41100 Larissa, Greece.
Life (Basel, Switzerland)
|April 27, 2024
概括
患有不安腿综合征/威利斯-埃克博姆病 (RLS/WED) 的老年人最初表现出语言缺陷. 然而,在研究期间,RLS/WED患者的认知差异在研究期间减少.
科学领域:
- 神经科学是一个神经科学.
- 老年学是指老年学的学科.
- 认知心理学 认知心理学
背景情况:
- 不安腿综合征/威利斯-埃克博姆病 (RLS/WED) 不一致地与认知障碍有关,特别是在语言和执行功能方面.
- 研究老年人与RLS/WED认知轨迹对于了解长期神经效应至关重要.
研究的目的:
- 为了检查老年人诊断出RLS/WED的纵向认知变化.
- 为了确定RLS/WED是否与老龄化人口的特定认知缺陷随着时间的推移有关.
主要方法:
- 利用了基于人口的HELIAD队列的数据,包括64岁以上的个人.
- 在没有痴呆症的参与者中,在基线和随访时评估认知领域 (记忆,视觉空间,注意力,执行功能,语言).
- 使用概括估计方程分析来评估RLS/WED对认知轨迹的影响.
主要成果:
- 1003名老年人 (平均年龄72.9岁) 患有RLS/WED (n=81) 和对照人被分析了大约3年.
- 两组之间在全球认知,记忆,注意力或执行/视觉感知技能方面没有发现显著差异.
- RLS/WED组表现出基线语言缺点 (0.249 SD),随着时间的推移 (0.063 SD) 减弱.
结论:
- 患有RLS/WED的老年人在基线时存在显著的语言缺陷.
- 在RLS/WED患者中观察到的语言缺点往往会随着时间的推移而减少并变得不那么明显.
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