液体反应与肝移植手术后成功断奶有关
Ricardo Castro1,2, Pablo Born1, Felipe Muñoz1
1Departamento de Medicina Intensiva, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago Centro, Santiago 8330074, RM, Chile.
Journal of personalized medicine
|April 27, 2024
概括
在自发呼吸试验 (SBT) 之前使用被动腿抬起 (PLR) 进行个性化流体管理,改善了肝移植患者的输出成功. 尽管流体平衡高,但对液体有反应的患者取得了更好的结果.
科学领域:
- 关键护理医学 关键护理医学
- 移植手术 移植手术
- 血液动力学 血液动力学
背景情况:
- 在ICU患者中,积极的液体平衡可能导致液体过载,器官功能障碍和死亡率增加.
- 肝移植 (LT) 患者经常经历高的术后液体平衡.
- 评估液体反应对于优化患者管理至关重要.
研究的目的:
- 调查在自发呼吸试验 (SBT) 之前通过被动腿抬起 (PLR) 引导的个性化流体管理是否可以减少具有高流体平衡的LT患者的输出失败.
- 在这个特定的患者队列中评估液体反应和输出输出结果之间的关联.
主要方法:
- 一项前性研究涉及15名在ICU的LT患者.
- 在ICU入院 (T1) 和SBT前 (T2) 使用PLR评估的液体反应能力.
- 在SBT之前和之后监测的心脏指数 (CI) 变化 (T3).
主要成果:
- 15名患者中有12名是SBT前 (T2) 具有流体反应的患者.
- 液体反应患者在SBT期间显示CI增加 (p=0.045).
- 在T2中,所有对液体有反应的患者都成功地被抽管,而2/3的不反应的患者有断奶困难.
结论:
- 基于PLR和SBT的个性化流体管理可以促进LT患者更早的断奶和成功的输出.
- 心血管评估对于管理患有高液体平衡的危急手术患者至关重要.
- 这种方法可以减轻与肝移植后流体过载相关的风险.
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