慢性牙周炎患者的腹膜腹和深部感染之间的关联:使用国家健康查队列的两个嵌套病例控制研究
So Young Kim1, Il Hwan Park2, Chun Sung Byun2
1Department of Anatomy and Cell Biology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Journal of clinical medicine
|April 27, 2024
概括
慢性牙周炎 (CP) 与更高的深感染 (DNI) 发病率有关,特别是在年轻,男性,低收入和农村人口中. 这凸显了需要主动管理CP以减轻DNI风险的必要性.
科学领域:
- 口腔健康 口腔健康
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 牙感染是导致深感染 (DNI) 的首要原因.
- 慢性牙周炎 (CP) 和DNI发病率之间的联系仍未得到充分探索.
- 这项研究调查了CP与DNI和腹腹 (PTA) 的发生之间的关联.
研究的目的:
- 评估CP病史患者中DNI和PTA的发生率.
- 为了确定DNI和PTA的CP的赔率比率.
- 根据人口统计,社会经济地位和并发症,分析CP-DNI关系中的子组变化.
主要方法:
- 使用了韩国国家医疗保险服务-全国样本队列 (2002-2019).
- 研究I:将4585名PTA患者与19340名对照人匹配,分析CP史.
- 研究II:将46,293名DNI患者与185,172名对照进行匹配,使用条件后勤回归分析CP史.
主要成果:
- 在CP史和PTA发病率 (调整后OR=1.28) 之间没有发现显著的关联.
- 史前的CP与增加的DNI发病率显著相关 (调整后OR=1.55).
- 在年轻,男性,低收入和农村人口中,CP-DNI关联更强.
结论:
- 之前的慢性牙周炎病史与韩国人口中更高的深感染发病率有关.
- 对患者来说,CP的有效管理至关重要,以减少患DNI的风险.
- 这些发现强调了牙周健康对传染病风险的系统影响.
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