年龄和中风严重程度对急性动脉样硬化并列病变的临床结果最为重要
Cyrill Huber1, Jatta Berberat2, Renske Sassenburg2
1Department of Neuroradiology, Kantonsspital Aarau, University of Zurich, Tellstrasse 21, 5001 Aarau, Switzerland.
Journal of clinical medicine
|April 27, 2024
概括
对急性缺血性中风双重病变的内血管治疗是安全有效的. 较年轻的中风和良好的康复治疗的年轻患者有更好的结果,而老年和并发病增加了死亡风险.
科学领域:
- 神经学 神经学
- 干预性神经辐射学
- 血管神经学 血管神经学
背景情况:
- 双重病变 (TLs) 占急性缺血性中风 (AIS) 的15-30%.
- 内血管治疗 (EVT) 是主要的疗法,但结果预测需要澄清.
- 在AIS中动脉样硬化TLs需要进一步调查以优化治疗.
研究的目的:
- 确定影响AIS患者的短期和长期结果的临床和人口因素,其中包括经过EVT的动脉硬化TL患者.
- 在这个特定的患者队列中分析功能结果和死亡率的预测因素.
- 评估EVT对动脉样硬化TLs的安全性和有效性.
主要方法:
- 对116名患有动脉硬化TLS的AIS患者进行了回顾性单中心队列研究.
- 对人口统计,程序和成像数据的分析.
- 评估功能性结果 (mRS 0-2) 和3个月后的死亡率.
主要成果:
- 中位数年龄72岁,女性31%;中位数NIHSS 14,中位数ASPECT 9.
- 在83%的患者中实现了良好的再通道化 (mTICI2b-3).
- 在40%的患者中,有利的结局 (mRS 0-2),28%的患者在3个月内死亡;年龄和NIHSS是强有力的预测因素.
- 糖尿病和以前的神经疾病独立预测了长期死亡率.
结论:
- 年龄较小,中风严重程度较低,成功的再道化与有利的结果相关.
- 年龄较大,中风严重程度较高,先前的神经系统疾病和糖尿病与死亡率增加有关.
- 针对急性动脉样硬化TLs的EVT是可行的,安全和有效的,具有已确定的结果预测因素.
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