Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Ligand Binding and Linkage00:49

Ligand Binding and Linkage

4.8K
Allosteric proteins have more than one ligand binding site; the binding of a ligand to any of these sites influences the binding of ligands to the other sites. When a protein is allosteric, its binding sites are called coupled or linked.  In the case of enzymes, the site that binds to the substrate is known as the active site and the other site is known as the regulatory site. When a ligand binds to the regulatory site, this leads to conformational changes in the protein that can influence...
4.8K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

The Binding of 3-O-Methylfluorescein Phosphate to the Catalytic Domain of the Human CDC25B Phosphatase: A Structural Investigation.

Chembiochem : a European journal of chemical biology·2026
Same author

Coordination of a Dirhodium(II) Center to Methionine and Cysteine Side Chains: Evidence from X-Ray Structure of the Adduct Formed by Dirhodium Tetraacetate with a C-Phycocyanin.

International journal of molecular sciences·2025
Same author

Cisplatin/Apo-Transferrin Adduct: X-ray Structure and Binding to the Transferrin Receptor 1.

Inorganic chemistry·2024
Same author

On the mechanism of action of arsenoplatins: arsenoplatin-1 binding to a B-DNA dodecamer.

Dalton transactions (Cambridge, England : 2003)·2024
Same author

Structural Insights into Protein-Aptamer Recognitions Emerged from Experimental and Computational Studies.

International journal of molecular sciences·2023
Same author

Steric hindrance and structural flexibility shape the functional properties of a guanine-rich oligonucleotide.

Nucleic acids research·2023

相关实验视频

Updated: Jun 27, 2025

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins
11:34

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins

Published on: August 9, 2019

6.6K

适合剂:功能结构研究和生物医学应用2.0

Romualdo Troisi1,2, Filomena Sica1

  • 1Department of Chemical Sciences, University of Naples Federico II, 80126 Naples, Italy.

International journal of molecular sciences
|April 27, 2024
PubMed
概括
此摘要是机器生成的。

本专题号探讨了阿普坦技术,重点关注新型阿普坦开发及其多样化的生物医学应用. 发现基于aptamer的诊断和治疗的尖端研究.

科学领域:

  • 生物化学和分子生物学
  • 生物医学工程 生物医学工程
  • 药物发现和开发 药物发现和开发

背景情况:

  • 本期专题基于先前对体的研究,强调其功能和结构特征的进步.
  • 它解决了对aptamers作为生物医学应用的多功能工具日益增长的兴趣.

更多相关视频

Selection of Aptamers for Amyloid β-Protein, the Causative Agent of Alzheimer's Disease
15:23

Selection of Aptamers for Amyloid β-Protein, the Causative Agent of Alzheimer's Disease

Published on: May 13, 2010

19.4K
Kinetic Screening of Nuclease Activity using Nucleic Acid Probes
06:52

Kinetic Screening of Nuclease Activity using Nucleic Acid Probes

Published on: November 1, 2019

8.3K

相关实验视频

Last Updated: Jun 27, 2025

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins
11:34

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins

Published on: August 9, 2019

6.6K
Selection of Aptamers for Amyloid β-Protein, the Causative Agent of Alzheimer's Disease
15:23

Selection of Aptamers for Amyloid β-Protein, the Causative Agent of Alzheimer's Disease

Published on: May 13, 2010

19.4K
Kinetic Screening of Nuclease Activity using Nucleic Acid Probes
06:52

Kinetic Screening of Nuclease Activity using Nucleic Acid Probes

Published on: November 1, 2019

8.3K