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Updated: Jun 27, 2025

Quantitative Measurement of γ-Secretase-mediated Amyloid Precursor Protein and Notch Cleavage in Cell-based Luciferase Reporter Assay Platforms
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通过ADAM17和γ-分泌酶蛋白分解处理调节梅特克表面表达

Kevin C Lahey1, Christopher Varsanyi1, Ziren Wang1

  • 1Department of Microbiology, Biochemistry and Molecular Genetics, Center for Cell Signaling, Rutgers New Jersey Medical School, 205 South Orange Ave, Newark, NJ 07103, USA.

International journal of molecular sciences
|April 27, 2024
PubMed
概括

由ADAM17和玛分泌酶进行的Mertk (Mer tyrosine kinase) 裂变是一种调节其水平的恒常性过程. 这种蛋白质分离调节可以防止单细胞和巨细胞中Mertk过度活化.

关键词:
在ADAM-17外域内发生脱落.气体6 是一个气体.梅尔特克是因为细胞内受体贩运 细胞内受体贩运膜表达的表达方式蛋白质溶解过程中的蛋白质溶解.γ-秘密的秘密

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