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了解功能神经障碍:最近的见解和诊断挑战

Ioannis Mavroudis^1,2, Dimitrios Kazis³, Fatima Zahra Kamal^4,5

¹Department of Neuroscience, Leeds Teaching Hospitals, NHS Trust, Leeds LS2 9JT, UK.

International journal of molecular sciences

|April 27, 2024

概括

功能神经障碍 (FND) 呈现出神经症状,没有明确的有机原因. 神经成像和理解FND的进展.

科学领域:

神经学神经学
神经科学是一个神经科学.
精神病学是一个精神病学.

背景情况:

功能神经障碍 (FND),以前称为转化障碍,涉及缺乏可识别的有机基础的神经症状.
症状表现为运动,感觉或认知障碍,严重程度各不相同,并不是故意产生的.
诊断依赖于临床评估,并排除其他医学或精神疾病.

研究的目的:

综合有关FND的当前知识,包括流行病学,病理生理学和临床表现.
探索神经成像对FND神经支和诊断挑战的洞察力.
区分FND与模仿,并讨论治疗的影响.

主要方法:

关于功能神经障碍的当前文献的综述.
对与FND相关的神经成像研究的分析.
检查 FND 的诊断标准和差异诊断.

主要成果:

FND表现出显著的表型异质性,这给诊断带来了挑战.
神经成像在了解FND的神经机制方面发挥着至关重要的作用.
区分FND与假装需要仔细的临床评估.

结论:

对FND的细微了解对于临床实践和研究至关重要.
神经成像技术的进步为个性化治疗策略提供了潜力.
未来的研究应该专注于FND的多面性质,以改善患者的治疗结果.

关键词:

差异诊断是一种差异诊断.流行病学流行病学功能性神经系统疾病功能性神经系统疾病神经成像是一种神经成像.病理生理学病理生理学现象型异质性的异质性

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