视觉脂肪组织深度作为妊娠糖尿病的新型预测因素:全面的元分析和系统审查
Weikun Li1, Yi Jiang1, Ling Feng1
1Department of Gynecology and Obstetrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430074, China.
Medicina (Kaunas, Lithuania)
|April 27, 2024
概括
孕期糖尿病 (GDM) 患者在怀孕早期具有更高的内脏脂肪组织 (VAT) 深度. 这一发现表明,增值税深度可以预测GDM风险,使及时干预成为可能.
科学领域:
- 产科和妇科 产科和妇科
- 代谢障碍 代谢障碍 代谢障碍
- 医疗成像医学成像
背景情况:
- 孕期糖尿病 (GDM) 的患病率正在上升.
- 身体质量指数 (BMI) 作为早期GDM预测指标具有局限性.
- 识别GDM早期怀孕预测因素对于及时干预至关重要.
研究的目的:
- 调查内脏脂肪组织 (VAT) 深度与GDM风险之间的关联.
- 评估增值税深度作为GDM的潜在早期怀孕预测因素.
主要方法:
- 七项研究的元分析,包括1315名女性 (225名有GDM).
- 在PubMed,Embase和Web of Science数据库中搜索到2023年9月30日.
- 采用随机效应模型来分析增值税深度和GDM概率之间的关系.
主要成果:
- 与非GDM女性相比,被诊断患有GDM的女性的增值税深度显著更高 (SMD:0.84;CI:0.52-1.15,p <0.001).
- 观察到显著的统计异质性 (I2 = 72.88%,p = 0.001),并确定并讨论了来源.
- 亚组分析表明,在不同的诊断标准和增值税定义中,GDM患者的增值税深度更高.
结论:
- 第一个三个月的GDM患者表现出相对于非GDM女性的增值税深度增加.
- 增值税深度成为怀孕早期GDM的潜在预测因素.
- 这项研究支持开发新的GDM预测因子,并强调早期干预策略.
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