相关实验视频

Updated: Jun 27, 2025

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

Published on: October 25, 2024

结核病和非结核性菌根性感染在患有脊髓关节炎的患者:一个基于人口的研究

Jiyoul Yang¹, Hyun-A Jang², Hyunjeong Cho³

¹Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Chungbuk National University Hospital, Cheongju 28644, Republic of Korea.

Medicina (Kaunas, Lithuania)

|April 27, 2024

概括

脊椎关节炎 (SpA) 患者不会面临Mycobacterium结核病 (MTB) 或非结核菌 (NTM) 感染的风险增加. 虽然生物药物可能会略微提高MTB风险,但主动查和预防有效地管理这些潜在的感染.

科学领域:

类风湿病学类风湿病学
传染性疾病传染性疾病
流行病学流行病学

背景情况:

脊椎关节炎 (SpA) 是一组慢性炎症性疾病,通常用生物药物治疗.
生物疗法可能会增加Mycobacterium结核病 (MTB) 和非结核菌 (NTM) 感染的风险.
了解SPA患者的感染风险对于安全治疗至关重要.

研究的目的:

为了比较MTB和NTM感染的发病率和风险,SPA患者与对照人群进行比较.
评估生物治疗对SPA患者感染风险的影响.

主要方法:

基于人口的队列研究,使用韩国国家医疗保险服务-国家样本队列 (2002-2019).
包括2333名SPA患者 (椎炎,牛皮关节炎) 和9332名匹配对照.
使用国际疾病分类-10码识别感染;使用Cox比例危险模型分析数据.

主要成果:

在SPA患者中,NTM (0.002%) 和MTB (0.016%) 的发生率微不足道,与对照组相比没有显著差异.
生物使用显示,NTM (5.66) 和MTB (3.069) 的发病率比率没有显著增加.
考克斯分析表明,在SPA患者中,MTB的显著调整危险比率 (1.479),在调整生物治疗后变得无意义.

结论:

在患有SpA.的患者中,NTM和MTB感染的风险没有增加.
生物治疗可能会略微增加MTB风险,但不会达到统计学上显著的发病率.
建议在使用生物药物的SPA患者进行潜在结核病和预防的积极查.

关键词:

结核病菌菌菌的结核病菌的结核病菌.结性脊柱炎是一种疾病.生物学是生物学的学科.没有结核的真菌细菌感染.牛皮关节炎牛皮关节炎

更多相关视频

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Published on: May 23, 2021

Author Spotlight: Evaluating Traditional Chinese Therapy for Ankylosing Spondylitis in Mice

Author Spotlight: Evaluating Traditional Chinese Therapy for Ankylosing Spondylitis in Mice

Published on: October 27, 2023

相关概念视频

Pulmonary Tuberculosis III

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:

Pulmonary Tuberculosis I

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...

Pulmonary Tuberculosis IV

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...

Pulmonary Tuberculosis V

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...

Pulmonary Tuberculosis II

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...

Other Pulmonary Disorders

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.