相关的预测因素与医院内性粉症的死亡率:一个队列研究
Sunee Chayangsu1, Chusana Suankratay2, Apichat Tantraworasin3,4
1Department of Internal Medicine, Surin Hospital, Surin 32000, Thailand.
Medicina (Kaunas, Lithuania)
|April 27, 2024
概括
梅里欧症是一种严重的感染,由Burkholderia pseudomallei引起,死亡率很高. 医院死亡的关键预测因素包括年龄较大,呼吸速度快,胸部X射线异常和低二氧化碳水平.
科学领域:
- 传染性疾病 传染性疾病
- 临床微生物学 临床微生物学
- 流行病学 流行病学
背景情况:
- 由Burkholderia pseudomallei引起的梅氏增生病在东南亚等热带地区普遍存在.
- 尽管有有效的治疗方法,但有机症的死亡率很高,特别是在感染性休克的情况下.
- 了解预后因素对于改善患者治疗结果至关重要.
研究的目的:
- 为了确定临床特征,微生物学的发现,和治疗结果在有机症患者.
- 确定与住院死亡率相关的因素,以更好地预测预后.
- 为了指导未来的治疗策略,为melioidosis.
主要方法:
- 泰国苏林医院对262名住院的有机症患者 (年龄大于15岁) 的回顾性队列研究 (2014年4月 - 2017年3月).
- 收录标准:阳性B. 伪菌培养.
- 后勤回归分析,以确定医院死亡的风险因素.
主要成果:
- 在262名患者中,有117人 (44.7%) 死亡. 平均年龄为57.2岁,73.7%是男性.
- 常见的并发病:糖尿病 (46.9%),慢性病 (13.4%),慢性肝病 (11.8%).
- 死亡的重要预测因素:年龄增加 (aOR 1.04),呼吸率升高 (aOR 1.18),胸部X射线异常 (aOR 4.79),CO2水平降低 (aOR 0.92).
结论:
- 年龄,呼吸速率,异常的胸部X射线检测结果和二氧化碳水平是患有乳腺炎的住院死亡率的重要预测因素.
- 医疗保健提供者应密切监测患有这些风险因素的患者.
- 对这些因素的认识可以为积极的治疗和患者管理策略提供信息.
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