精神病菌和微生物群-肠-大脑轴:我们从这里走到哪里?
Sylvie Binda1,2, Annie Tremblay2, Umar Haris Iqbal2
1Lallemand Health Solutions, 19 Rue des Briquetiers, BP 59, 31702 Blagnac, France.
Microorganisms
|April 27, 2024
概括
精神生物或有益的微生物可以影响微生物群-肠-大脑轴 (MGBA). 需要进一步的研究来了解它们的机制和在神经精神疾病中的应用.
科学领域:
- 神经胃肠病学 神经胃肠病学
- 微生物组研究的研究.
- 精神病学是一个精神病学.
背景情况:
- 微生物群-肠-大脑轴 (MGBA) 描述了肠道微生物与神经系统之间的双向通信.
- 这个轴影响生理功能,包括免疫力,情绪,睡眠和消化.
- 精神生菌是一种益生菌,具有调节MGBA的潜力.
研究的目的:
- 审查当前对精神生物制剂的理解,以及它们在调节MGBA中的作用.
- 突出心理生物应用未来研究的关键领域.
- 讨论使用益生菌治疗神经精神疾病的局限性.
主要方法:
- 现有文献的叙述性审查.
- 对未来的研究方向的展望.
- 讨论菌株级益生菌研究.
主要成果:
- 越来越多的证据支持益生菌的全身有益作用.
- 精神生物药物显示出管理各种健康方面的潜力.
- 许多精神生物效应的作用机制需要进一步描述.
结论:
- 益生菌,特别是精神生菌,为MGBA提供了有前途的治疗途径.
- 目前的应用存在显著的局限性,特别是在神经精神疾病中.
- 菌株特定的研究对于优化益生菌疗效至关重要.
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