对儿童系统性Bartonella henselae感染的回顾性分析
Ramona Florina Stroescu1,2, Flavia Chisavu2,3, Ruxandra Maria Steflea1,2
1Department XI of Pediatrics-1st Pediatric Discipline, Center for Research on Growth and Developmental Disorders in Children, "Victor Babes" University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania.
Microorganisms
|April 27, 2024
概括
儿童患有系统性Bartonella henselae感染 (猫病) 经常出现发烧和淋巴腺病,经常与猫接触有关. 早期诊断和阿兹菌素治疗对于有效的管理至关重要.
科学领域:
- 儿童传染病 儿童传染病
- 细菌学 细菌学是一门学科.
- 动物传播感染 动物传播感染
背景情况:
- 系统性Bartonella henselae感染,或猫病 (CSD),由于各种症状和血清学交叉反应性,造成了诊断挑战.
- 准确的诊断和及时的治疗对于儿科患者至关重要.
研究的目的:
- 追溯分析儿科系统性B. henselae感染的流行病学,临床,实验室和成像特征.
- 增强对儿童中心脏病的理解,促进诊断和治疗.
主要方法:
- 在罗马尼亚蒂米索拉,对确诊的儿科B. henselae感染 (2014-2024) 进行了十年的回顾性研究.
- 纳入标准:与动物接触,长期发烧,血液学/肝的症状,阳性血清学.
- 数据分析包括临床表现,实验室结果,成像和治疗结果.
主要成果:
- 19名儿科患者 (平均年龄8.1岁) 患病94.7%的猫科动物暴露.
- 常见的症状:发烧 (47.4%),淋巴腺病 (78.9%).
- 升高的ESR/CRP,高的B. henselaeIgM (63.2%) 和IgG (94.7%) 血清阳性. 常见的共同感染被注意到.
结论:
- 儿科系统性B. henselae感染通常表现为发烧和淋巴腺病,与猫接触密切相关.
- 实验室和成像检测结果有助于诊断,但潜在的共感染使得诊断复杂化.
- 阿齐思罗米是有效的;在发烧的儿童与猫接触时,早期考虑CSD至关重要.
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