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乳酸的生产由Lactiplantibacillus plantarumAC 11S-动力学和建模

Petya Popova-Krumova¹, Svetla Danova², Nikoleta Atanasova²

¹Institute of Chemical Engineering, Bulgarian Academy of Sciences, 103 Acad. G. Bontchev Str., 1113 Sofia, Bulgaria.

|April 27, 2024

概括

这项研究使用Lactiplantibacillus plantarum AC 11S优化了乳糖的乳酸生产,找到最佳条件和数学模型. 该模型准确地描述了细菌生长,基质消耗和产品形成,有助于未来的发酵过程.

科学领域:

生物技术是生物技术.
工业微生物学工业微生物学
化学工程是化学工程的重要组成部分.

背景情况:

乳酸是一种重要的工业化学品,具有多样化的应用.
通过微生物发酵优化其生产对于各种行业至关重要.
特定细菌菌株从乳糖中产生乳酸需要详细的动态分析.

研究的目的:

通过使用 Lactiplantibacillus plantarum AC 11S. 来研究从乳糖中产生乳酸的生产.
为了确定最佳的发酵条件 (pH,温度,基质度).
开发和验证细菌生长,基质消耗和乳酸形成的数学模型.

主要方法:

使用Lactiplantibacillus plantarum AC 11S的发酵实验,使用不同度的乳糖.
确定细菌生长和乳酸产量的最佳pH值和温度.
开发一个非结构化的数学模型,包括增长,消费和生产动力学,包括产品抑制.

主要成果:

乳酸生产的最佳条件是pH 6.5和30°C.
乳酸生产主要与生长相关.
在初始乳糖度超过15g/L时观察到产品抑制.
一个包含产品抑制的修改后勤方程最好地描述了整个过程的实验数据.

结论:

这项研究成功地利用L. plantarum AC 11S优化了从乳糖中生产的乳酸.
开发的动力模型为理解和预测发酵性能提供了一个强大的框架.
这些发现支持开发可控和连续的发酵工艺,以提高乳酸产量.

关键词:

牛奶植物植物菌植物植物 (Lactiplantibacillus plantarum) 是一种植物.增长的增长增长的增长增长的增长.乳酸乳酸是什么意思乳酸是什么意思乳糖乳糖是什么意思乳糖是什么意思数学建模的数学建模

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