炎症性肠病中的食纤维:我们是否准备好改变范式?
Laura Loy1, Lorenzo Petronio2, Giacomo Marcozzi2
1IBD Unit, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy.
Nutrients
|April 27, 2024
概括
食纤维对炎症性肠病 (IBD) 有好处,但患者往往会避开它们. 需要更多关于IBD管理和耐受性最佳纤维摄入量的研究.
科学领域:
- 胃肠病学和营养科学 胃肠病学和营养科学
背景情况:
- 临床前和临床研究表明,食纤维有益于炎症性肠病 (IBD).
- 由于症状管理,许多IBD患者限制纤维摄入量,尽管支持这种长期的证据有限.
- 目前的指导方针建议对IBD摄入足够的纤维,但最佳类型和数量仍然不清楚.
研究的目的:
- 审查饮食纤维及其与IBD相关的特征.
- 分析各种IBD临床环境中纤维消费对纤维消费影响的现实研究.
- 确定IBD中纤维摄入的未来研究方向.
主要方法:
- 现有文献的叙述性审查.
- 临床前和临床研究的分析.
- 对IBD中食纤维的真实数据的检查.
主要成果:
- 证据支持纤维在IBD中的益处,但患者的实践往往与此相矛盾.
- 关于IBD患者有益和可容忍的特定类型和数量的纤维存在缺乏清晰度.
- 关于IBD中纤维消耗的现实数据对于实际的饮食建议至关重要.
结论:
- 食纤维对IBD具有治疗潜力,需要重新评估当前的患者实践.
- 进一步的研究是必不可少的,以定义最优的纤维战略,以IBD管理量身定制.
- 未来的研究应该专注于表征富含纤维的食物消费,并促进IBD人群的充足摄入量.
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