分析基于树脂的牙科材料的成分,根据其临床应用
Claire-Adeline Dantagnan1,2, Sylvie Babajko3, Ali Nassif2,3
1Innovative Dental Materials and Interfaces Research Unit, Faculty of Dentistry, Université Paris Cité, 1 rue Maurice Arnoux, 92120 Montrouge, France.
Polymers
|April 27, 2024
概括
大多数牙科树脂含有双A (BPA) 衍生物,儿童用材料中比例较高. 这引发了人们对潜在的健康影响的担忧,特别是在脆弱人群中.
科学领域:
- 牙科材料科学 牙科材料科学
- 毒理学 毒理学 毒理学
- 公共卫生 公共卫生
背景情况:
- 基于树脂的牙材料在修复性牙科中被广泛使用.
- 双A (BPA) 和其衍生物是这些材料中常见的成分.
- 人们担心BPA衍生品对健康的潜在影响,尤其是对敏感群体.
研究的目的:
- 分析2023年欧洲市场上可用的基于树脂的牙科材料的单体成分.
- 量化这些材料中双A (BPA) 衍生物的流行程度.
- 研究BPA衍生物含量与材料应用之间的关系,特别是在儿科牙科中.
主要方法:
- 在欧盟和英国,对制造商网站进行基于树脂的牙科材料的全面搜索.
- 材料安全数据表 (MSDS) 用于确定单体成分.
- 公共医学数据库搜索补充了数据收集.
- 分析了543种材料组成.
主要成果:
- 分析的牙科材料中有70.3%含有BPA衍生物.
- 比斯-GMA (56.2%) 和比斯-EMA (28%) 是最常被检测到的BPA衍生物.
- UDMA (56.9%) 和TEGDMA (53.8%) 也是普遍存在的单体.
- 儿童牙科护理材料显示BPA衍生物单体度最高.
- 只有不到三分之一的材料没有BPA衍生物.
结论:
- 目前,绝大多数基于树脂的牙科材料都含有BPA衍生物.
- 这些材料的应用,特别是在儿科牙科中,需要进一步研究,因为BPA衍生物含量较高.
- BPA衍生单体对健康的潜在长期影响需要考虑预防原则,并为风险人群,包括儿童和孕妇或哺乳妇女,探索替代材料.
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