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Updated: Jun 27, 2025

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优化帕克利塔塞尔口服吸收和生物可用性:通过超临界抗溶剂流化床技术进行TPGS联合涂层

Zicheng Zhong1, Yanling Lan1, Jinxing Chen1,2

  • 1School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, 232 University City Ring Road East, Panyu District, Guangzhou 510006, China.

Pharmaceuticals (Basel, Switzerland)
|April 27, 2024
PubMed
概括

超临界抗溶剂流化床 (SAS-FB) 涂层增强了帕克利塔塞尔 (PTX) 对难溶性药物的生物可用性. 这项技术显著提高了药物输送和治疗疗效 in vivo.

关键词:
这是一个TPGS系统.生物可用性 生物可用性口服吸收 口服吸收帕克利塔克塞尔 (paclitaxel) 是一种药物.超临界的抗溶剂流化床是超临界的.

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