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Updated: Jun 27, 2025

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions
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在单克隆抗体配方中对基贝塔-环氧德 (HPβCD) 和多酸盐的联合作用的调查

Jiayi Huang1, Shiqi Hong1, Lucas Yuan Hao Goh1

  • 1Pharma Applied Sciences, Roquette Asia Pacific Pte Ltd., Singapore 138588, Singapore.

Pharmaceuticals (Basel, Switzerland)
|April 27, 2024
PubMed
概括

与多酸盐相结合的基贝塔-环氧德克斯特林 (HPβCD) 显著减少单克隆抗体 (mAb) 配方中的聚合和可分辨粒子,改善蛋白质的稳定性.

关键词:
克莱普托斯 (KLEPTOSE) 是一种HPβCD的药物.这是bevacizumab的治疗方法.辅助剂是一种辅助剂.基烯基β-循环环德克斯特林.这里是 ipilimumab 的所在地.这是一种单克隆抗体.聚酸盐是一种聚酸盐.这是一种蛋白质配方.蛋白质的稳定性 蛋白质的稳定性

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