一种新的IRAK4抑制剂DW18134 改善腹膜炎和炎症性肠病

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Updated: Jun 27, 2025

Induction of Intestinal Inflammation by Adoptive Transfer of CBir1 TCR Transgenic CD4+ T Cells to Immunodeficient Mice
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Induction of Intestinal Inflammation by Adoptive Transfer of CBir1 TCR Transgenic CD4+ T Cells to Immunodeficient Mice

Published on: December 16, 2021

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Yuqing Huang1,2, Yi Ning3,4, Zhiwei Chen4,5

  • 1Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan 528400, China.

Molecules (Basel, Switzerland)
|April 27, 2024
PubMed
概括

一种新型的小分子抑制剂,DW18134,有效地向IRAK4 (介素-1受体关联激酶4) 以减少炎症. 这种化合物对治疗自身免疫性疾病,如腹膜炎和炎症性肠病 (IBD) 是有前途的.

关键词:
这是一种IRAK4抑制剂.炎症性肠病 (IBD) 是一种炎症性肠病.巨细胞是一个巨细胞.膜炎是一种膜炎.

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