涉嫌北卡罗来纳州假药涉及的死亡,2020-2022年
Laura W Friederich1, Mary E Cox2, Brian E Hyson3
1Toxicology Department, North Carolina Office of the Chief Medical Examiner, 4312 District Dr, Raleigh, NC 27607, United States.
Journal of analytical toxicology
|April 27, 2024
概括
含有意想不到物质的假药在北卡罗来纳州造成死亡. 法医毒理学在2020-2022年期间的75例病例中发现了新型二,突出显示了显著的公共卫生风险.
科学领域:
- 法医毒理学 法医毒理学
- 公共卫生 公共卫生
- 药品分析 药品分析
背景情况:
- 假冒药片对公共健康构成重大危险,通常模仿处方药.
- 调查结果和现场证据可能表明假药消费,但毒理学分析对于确认至关重要.
- 北卡罗来纳州首席法医办公室遇到可疑的死亡事件,报告了处方药的消费,但未经毒理学证实.
研究的目的:
- 描述2020年至2022年北卡罗来纳州涉嫌假药死亡的背景和特征.
- 告知法医科学界,执法部门和公共卫生利益相关者关于这种新出现的威胁.
- 提高个人消费假冒药物的风险的意识.
主要方法:
- 分析了从2020年1月到2022年12月的75个病例的方便样本.
- 据报道,一些病例涉及处方药 (阿尔普拉佐拉姆,氧化,可) 被消费的死亡,但毒理学分析显示出意想不到的物质.
- 审查了死亡现场调查,尸检结果和毒理学报告.
主要成果:
- 确定了75起涉嫌假药死亡的案例.
- 毒理学分析揭示了新型的二类药物,如flualprazolam,etizolam和bromazolam,以及预期的阿片类药物和alprazolam.
- 药丸是通过个人联系,非法街头销售或在线购买获得的.
- 消费方法包括口服和吸气.
- 一些死者意识到药丸的潜在假冒性质.
结论:
- 假冒的处方药,特别是那些含有新型精神活性物质的药物,如二,是北卡罗来纳州可疑死亡的重要原因.
- 该研究强调了全面毒理学分析在识别假冒物质和了解它们在死亡率中的作用方面的重要性.
- 法医毒理学家,执法部门和公共卫生官员之间的加强合作对于解决这一公共卫生危机至关重要.
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