SARS-Cov-2 感染:一个新的垂体中风风险因素?
Alberto Ragni1, Giulia Bendotti1, Emilia Biamonte1
1Endocrinology and Metabolic Diseases Unit, SS. Antonio e Biagio e Cesare Arrigo Teaching Hospital, Alessandria, Italy.
Endocrine, metabolic & immune disorders drug targets
|April 27, 2024
概括
感染COVID-19可能会使个体易患下垂体中风 (PA),这是一种涉及下垂体出血或缺血的疾病. 这种风险在两个案例中得到了突出说明,一个是存在血管因子,另一个是没有血管因子的年轻患者.
科学领域:
- 内分泌学 在内分泌学.
- 神经学 神经学
- 传染性疾病 传染性疾病
背景情况:
- 垂体脑梗塞 (PA) 是一种临床综合征,由垂体腺的出血或缺血引起.
- 在PA中出现突然的头痛,视力缺陷和下垂体.
- COVID-19已与血管并发症有关,新出现的证据表明与PA的联系.
研究的目的:
- 为了调查COVID-19感染与垂体瘤发作之间的潜在关联.
- 介绍两个不同的案例,说明COVID-19背景下的PA.
主要方法:
- 在COVID-19感染后出现PA的两名患者的病例报告分析.
- 临床评估包括荷尔蒙测定和神经成像 (细胞MRI).
- 手术干预 (透膜切除) 和临床随访.
主要成果:
- 案例1:一名64岁的男性患有并发症,在COVID-19后患有出血性宏腺瘤的PA,经历了手术后持续的视觉症状.
- 案例2:一个没有先前危险因素的18岁女性在COVID-19后发展出PA,症状完全消失,手术后荷尔蒙恢复.
- 这两种情况都强调了COVID-19后的PA发展潜力,无论传统的风险因素如何.
结论:
- 除了高血压和抗凝血等既定因素之外,COVID-19可能是脑下垂体中风的新兴危险因素.
- 在年轻的个体中,可以发生PA,而没有先导性条件,正如第二个案例所示的那样.
- 这些病例突出了与COVID-19相关的PA的不同临床表现和结果.
关键词:
在 COVID19 疫情下,假定存在的原因是hypophysis.这是一种hypopituitarism.下垂体腺瘤的前列腺瘤.pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary pituitary通过形外科手术.更多相关视频
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