Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Positron Emission Tomography01:29

Positron Emission Tomography

4.2K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
4.2K
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

112
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
112

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

[<sup>18</sup>F]FDG functional PET revisited: A new perspective on the temporal dynamics of brain glucose metabolism.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism·2026
Same author

Prognostic Value of <sup>18</sup>F-FDG and <sup>18</sup>F-FEC Uptake in Hepatocellular Carcinoma Using Contrast-Enhanced Integrated PET/MRI: Correlation with Histology and Survival.

Cancers·2026
Same author

Active Brown Adipose Tissue Is Associated With Reduced Arterial Inflammation and Less Atherogenic Circulating Factors in Individuals With Obesity.

Arteriosclerosis, thrombosis, and vascular biology·2026
Same author

Assessing vascular inflammation during continuous TSH suppression in differentiated thyroid cancer: a longitudinal [<sup>18</sup>F]FDG PET/CT analysis.

EJNMMI research·2026
Same author

High-temporal resolution metabolic connectivity resolved by component-based noise correction.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism·2026
Same author

Uptake Patterns of [<sup>18</sup>F]Fluoroestradiol PET/MRI in Benign Breast Lesions and Molecular Breast Cancer Subtypes.

Cancers·2026

相关实验视频

Updated: Jun 27, 2025

Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function
10:21

Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function

Published on: August 8, 2019

8.3K

对心脏图像衍生输入函数的验证,用于功能性PET量化.

Murray Bruce Reed1,2, Patricia Anna Handschuh1,2, Clemens Schmidt1,2

  • 1Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.

European journal of nuclear medicine and molecular imaging
|April 27, 2024
PubMed
概括

这项研究引入了一种用于脑功能PET (fPET) 成像的新型非侵入性方法. 这种新的心脏输入功能协议准确地量化了大脑活动,改进了传统方法.

关键词:
6-[18F]---l-dopa (6-[18F]FDOPA) 的含量可能会增加.动脉输入函数 (AIF) 是一个动脉输入函数.功能性正子辐射断层扫描 (fPET)图像衍生输入函数 (IDIF) 是指图像衍生输入函数.[18F]2-二-脱氧-D-葡萄糖 ([18F]FDG) 是一种[18F]2-二-脱氧-D-葡萄糖.

更多相关视频

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
11:09

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

Published on: December 16, 2022

3.7K
Radiosynthesis, Quality Control, and Small Animal Positron Emission Tomography Imaging of 68Ga-Labelled Nano Molecules
09:55

Radiosynthesis, Quality Control, and Small Animal Positron Emission Tomography Imaging of 68Ga-Labelled Nano Molecules

Published on: October 4, 2024

360

相关实验视频

Last Updated: Jun 27, 2025

Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function
10:21

Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function

Published on: August 8, 2019

8.3K
High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
11:09

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

Published on: December 16, 2022

3.7K
Radiosynthesis, Quality Control, and Small Animal Positron Emission Tomography Imaging of 68Ga-Labelled Nano Molecules
09:55

Radiosynthesis, Quality Control, and Small Animal Positron Emission Tomography Imaging of 68Ga-Labelled Nano Molecules

Published on: October 4, 2024

360

科学领域:

  • 神经成像是一种神经成像.
  • 放射化学 放射化学是指辐射化学.
  • 核医学就是核医学.

背景情况:

  • 功能性PET (fPET) 能够动态研究大脑新陈代谢和神经递质信号.
  • 在fPET中准确量化需要动脉输入函数 (AIF),通常通过侵入性动脉血液采样获得.
  • 非侵入性图像衍生输入函数 (IDIF) 在空间分辨率和视野方面存在局限性.

研究的目的:

  • 开发和验证使用心脏IDIF进行脑fPET的新型扫描协议.
  • 克服传统IDIF在脑成像中的局限性.
  • 为了能够准确,非侵入性量化大脑活动的动态变化.

主要方法:

  • 20名健康参与者使用FDG或6-FDOPA进行了fPET/MR扫描.
  • 一个使用床上移动穿的新协议捕获了心脏IDIF和大脑任务诱导的变化.
  • 来自各种血液池和复合物的图像衍生输入函数 (IDIF) 与金标准动脉输入函数 (AIF) 进行了比较.

主要成果:

  • 在IDIF和AIF之间观察到中等到高的协议 (r:0.60-0.89).
  • 复合IDIF (3VOI和3VOIVB) 显示与AIF的协议有所改善 (r:0.87-0.93).
  • 这两种方法都显示了同等的定量值和与AIF衍生计量的高度一致 (r:0.975-0.998).

结论:

  • 拟议的协议允许准确的非侵入性估计大脑fPET的输入功能.
  • 这种方法可以充分量化特定任务的变化,克服IDIF的局限性.
  • 这些进步简化了临床研究,增加了患者的舒适性,并且适用于任何PET扫描仪.