胃穿孔活检:它已经过时了吗?
Petre Francois Steyn1, Otto Karusseit2
1Department of Surgery, University of Pretoria Medical School, Pretoria, South Africa.
Langenbeck's archives of surgery
|April 27, 2024
概括
自发胃穿孔的常规活检不太可能检测出癌症. 胃穿孔活检的组织学评估没有发现恶性瘤,这表明活检可能在康复后更好地进行内镜检查.
科学领域:
- 胃肠病学 胃肠病学
- 手术病理学手术病理学
背景情况:
- 自发胃穿孔是一个关键的手术紧急情况.
- 在这些情况下,进行手术内活检以排除恶性瘤的必要性是有争议的.
研究的目的:
- 为了评估从自发胃穿孔检测癌症的手术内活检的诊断产量.
主要方法:
- 一项前性观察性研究包括连续出现自发胃穿孔的患者.
- 从穿孔边缘的活检进行了组织学检查,以确定上皮质类型和病理学.
主要成果:
- 分析了68名患者;88%的胃粘膜活检,48%的胃粘膜活检是特定类型的.
- 所有活检都显示良性,没有在手术内检测到恶性瘤.
- 在随后的胃镜随访中没有发现恶性瘤.
结论:
- 针对自发性胃穿孔的常规手术内活检可能不需要用于癌症排除.
- 建议在患者康复后进行内镜活检作为一种可能更有效的方法.
相关概念视频
01:28Esophageal Perforation-II: Clinical Manifestations and Management
57
Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
Clinical Manifestations:
57
01:22Esophageal Perforation-I: Introduction
90
Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
90
01:28Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
115
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
115