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用AngioTool软件量化2型黄斑远程切除症中的血管变化

Indu Govindaraj¹, Maanasi Mahalingam¹, Uma Maheswari¹

¹Department of Vitreo-Retina Services, Aravind Eye Hospital, Chennai, Tamil Nadu, India.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

|April 27, 2024

概括

麦克泰尔2眼睛的血管参数 (VP) 与正常眼睛有很大差异,但与视力敏度无关. AngioTool (AT) 可以量化疾病的进展.

科学领域:

眼科医生眼科眼科
医疗成像医学成像
视网膜疾病视网膜疾病

背景情况:

斑点电脉切开症2型 (MacTel2) 是一种视网膜血管疾病.
在MacTel2中对血管变化的定量分析对于了解疾病进展至关重要.

研究的目的:

使用AngioTool (AT) 将MacTel2眼睛和正常眼睛之间的血管参数 (VP) 进行比较.
评估VP和最佳校正视敏度 (BCVA) 之间的相关性.
在简单的麦克泰尔分类的不同等级中分析VP.

主要方法:

使用 SD OCTA 图像对表面 (SVC) 和深层毛细管复合体 (DVC) 的回顾性研究.
使用Image J和AngioTool (AT) 进行的图像分析.
评估的参数包括探索面积 (EA),船舶面积 (VA),船舶百分比面积 (VPA),连接点总数 (TNJ),连接点密度 (JD),船舶总长度 (TVL),船舶平均长度 (AVL),终点总数 (TNE) 和平均E缺口 (MEL).

主要成果:

在大多数VP中,在MacTel2和正常眼睛之间观察到显著的差异,不包括两个复合体中的EA和TNE.
在任何VP和BCVA之间没有发现相关性.
跨象限分析显示了VPA,AVL和JD (SVC) 和AVL,TNE,JD和VPA (DVC) 的显著差异.
后期分析显示TNJ,JD,TVL和AVL在1级和3级 (SVC) 之间存在显著差异,VA,VPA,TNJ,JD,TVL和MEL在0级和3级 (DVC) 之间存在显著差异.

结论:

在MacTel2眼中,血管参数受到显著影响.
VP与BCVA没有相关性,这表明视力敏度不是血管变化的直接指标.
颜色是MacTel2进展的一个关键因素.
在MacTel2.2,AngioTool (AT) 显示出作为一种量化测量疾病进展的工具的潜力.

关键词:

血管工具是血管工具.图像J 图像J 图像J 麦克泰尔是什么意思视网膜血管参数视网膜血管参数

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