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Updated: Jun 27, 2025

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
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CB1受体阴性全调节器Org27569对小鼠中氧化戒断症状的影响

Rhianne L Scicluna1,2, Nicholas A Everett1,2, Connie J Badolato1,2

  • 1Brain and Mind Centre, The University of Sydney, 94 Mallet Street, Camperdown, Sydney, NSW, 2050, Australia.

Psychopharmacology
|April 27, 2024
PubMed
概括

这项研究发现,Org27569,一种大麻素受体1型 (CB1R) 阴性全调节剂,没有有效地减少小鼠的阿片类药物戒断症状. 它的效果被运动和胃肠道运动的影响所混.

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