缺食症是病毒性肺炎严重程度的一个未被认可的危险因素
Michael S Pulia1,2, Rachelle Herrin3, Raele Donetha Robison4,5
1BerbeeWalsh Department of Emergency Medicine, University of Wisconsin Madison School of Medicine and Public Health, 800 University Bay Drive Suite 310, Madison, WI, 53705, USA. mspulia@medicine.wisc.edu.
已经存在的消化不良会增加50岁以上成年人患重症COVID-19的风险. 这种情况独立地与老年患者的COVID-19严重性得分较高有关.
科学领域:
- 老年学是指老年学的学科.
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- COVID-19对老年人构成重大风险.
- 消化不良或吞困难是老年人群中常见的并发症.
研究的目的:
- 调查是否先前存在的消化障碍是严重COVID-19结果的危险因素.
- 在50岁及以上的成年人中分析食障碍和COVID-19严重程度之间的关联.
主要方法:
- 一项回顾性队列研究,使用来自中西部两个急诊室 (ED) 的电子健康记录.
- 纳入标准:年龄≥50岁的患者,在ED访问期间检测出SARS-COV-2阳性.
- 主要结果:世界卫生组织COVID-19临床严重性得分最高 (≥4被认为是严重的) 在ED到达30天内.
主要成果:
- 患有消化不良症的患者 (n=40) 比没有消化不良症的患者更有可能患上严重的COVID-19 (65.0%对41.3%,p=0.015).
- 多变量分析显示,先前存在的消化不良 (OR 2.38) 和糖尿病 (OR 2.42) 独立地与严重COVID-19的几率增加有关.
结论:
- 预先存在的消化不良症是50岁及以上成年人严重COVID-19的独立风险因素.
- 在评估老年患者的COVID-19风险时,医疗保健提供者应考虑食障碍状态.
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