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Updated: Jun 27, 2025

Analysis of Combinatorial miRNA Treatments to Regulate Cell Cycle and Angiogenesis
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Analysis of Combinatorial miRNA Treatments to Regulate Cell Cycle and Angiogenesis

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CARM1高甲基化NuRD染色体重塑复合物,促进细胞周期基因表达和乳腺癌的发展

Xue Chen1,2,3, Ming-Feng Huang1,2, Da-Meng Fan1,2,3

  • 1State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiang'an South Road, Xiamen, Fujian 361102, China.

Nucleic acids research
|April 27, 2024
PubMed
概括

蛋白质氨酸甲基转移酶CARM1在NuRD复合体中甲基化GATAD2A/2B,激活细胞循环进展的基因. 针对这种甲基化抑制了乳腺癌的生长,提供了潜在的治疗策略.

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