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Updated: Jun 27, 2025

Analysis of Spliceosomal snRNA Localization in Human Hela Cells Using Microinjection
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Analysis of Spliceosomal snRNA Localization in Human Hela Cells Using Microinjection

Published on: August 6, 2019

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一种特定于线虫的核糖核蛋白复合体调解主要线虫拼接领导者snRNP及其目标前mRNA之间的相互作用

Peter Eijlers1, Mohammed Al-Khafaji1, Eva Soto-Martin1

  • 1School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Institute of Medical Sciences, Foresterhill, Aberdeen AB25 2ZD Scotland, UK.

Nucleic acids research
|April 27, 2024
PubMed
概括

研究人员发现,线虫特异性蛋白质SNA-3和SUT-1与SmYRNAs形成复合体,对线虫生存能力和拼接领导者跨拼接至关重要. 这种SmY小核核核糖核蛋白 (snRNP) 复合体将SL1 snRNP招募到新生的转录物中,从而促进跨拼接体组装.

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