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对患有骨髓扩散性瘤的患者的直接和间接成本

Jingbo Yu¹, James Nelson², Taylor Marlin²

¹Incyte Corporation, Wilmington, DE, USA.

Leukemia & lymphoma

|April 27, 2024

概括

骨髓增殖性瘤 (MPNs) 显著增加医疗保健成本和生产力损失. 与对照组相比,MPN患者的直接医疗费用和残疾相关费用较高.

科学领域:

血液学血液学血液学
卫生经济学卫生经济学

背景情况:

骨髓增殖性瘤 (MPNs) 代表了一组与显著发病率相关的疾病.
众所周知,这些情况会影响医疗保健资源利用率和经济生产率.

研究的目的:

量化与骨髓纤维化 (MF),真多细胞血症 (PV) 和基本血小板血 (ET) 相关的直接和间接医疗保健成本.
评估被诊断为MPNs的患者的经济负担,包括残疾假.

主要方法:

使用残疾假期和医疗索赔数据进行回顾性队列分析.
在MF,PV,ET患者和匹配的对照组之间比较医疗费用.
对患有血栓事件的患者进行亚组分析.

主要成果:

在所有研究的MPN类型中,MPN病例的总医疗费用明显高于对照病例 (MF: $67,456; PV: $10,970; ET: $22,279).
患有MPN的患者更有可能采取残疾假期,从而承担更多与残疾相关的费用.
血栓事件进一步提高了MPN子组的直接和间接成本,特别是PV和ET.

结论:

骨髓增殖性瘤给医疗保健系统和个人带来了巨大的经济负担.
残疾和血栓事件显著导致与MPNs相关的成本增加.
这些发现强调了在MPN护理中需要全面的成本管理策略.

关键词:

骨髓增殖性瘤是一种多发性瘤.在残疾假期期间,残疾人可以享受残疾假.医疗保健费用医疗保健费用医疗保健利用率医疗保健利用率间接成本间接成本间接成本血小板细胞血症的发生.

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