临床和放射性风险因素导致自发肌肉血液瘤患者的不良结果
Federico Orsini1, Giorgio Mazzotta1, Luigi Carbone2
1Department of Diagnostic Imaging, Oncological Radiotherapy and Hematology - Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.
European journal of radiology
|April 27, 2024
概括
在CT扫描和晚年时,自发肌肉血瘤大于5.5厘米,预测结果不佳. 抗凝固药物治疗似乎在自发肌肉血液瘤的结果中起到很小的作用.
科学领域:
- 紧急医疗 紧急医疗
- 放射学 放射学是一门学科.
- 内部医学 内部医学
背景情况:
- 自发肌肉血液瘤 (SMH) 在急诊室 (ED) 很常见,通常与抗凝药有关.
- 目前的ED管理缺乏SMH的标准指南.
- 确定不良结果的预测因素对于有效的患者管理至关重要.
研究的目的:
- 确定与SMH患者的不良结果相关的临床和放射性参数.
- 建立在ED中SMH风险分层的标准.
主要方法:
- 一个城市教学医院的回顾性观察队列研究 (2016-2019).
- 多变量后勤回归和ROC分析,以确定不良结果的预测因素 (需要治疗或住院治疗).
- 分析的参数包括血液瘤大小,抗凝血,年龄和查尔森并发症指数 (CCI).
主要成果:
- 总共包括231名患者 (平均年龄67岁);54.1%的人服用抗凝药.
- 在CT扫描上,SMH直径>5.5厘米独立地与糟糕的结果相关 (OR 4.009,p=0.001).
- 高龄也是不良结果的独立预测因素 (OR 1.035,p=0.033),而抗凝药显示起了较小的作用.
结论:
- SMH直径>5.5厘米和晚年是不良结果的重要预测因素.
- 这些发现可以帮助在ED中对SMH进行风险分层和管理决策.
- 抗凝剂治疗对SMH结局的作用可能不如以前想象的那么重要.
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