随机自控研究比较开放式面部与封闭式固定化面具在分片骨放射治疗中的随机自控研究
Michèle Keane1, Nienke Weitkamp1, Indira Madani1
1Department of Radiation Oncology, University Hospital Zürich and University of Zürich, Rämistrasse 100, 8091, Zürich, Switzerland.
概括
与封闭面罩相比,开放面罩在骨放射治疗期间显著降低了患者的不适和疼痛. 这种改善的舒适性不会影响患者在治疗期间定位或固定运动的准确性.
科学领域:
- 辐射瘤学 辐射瘤学
- 医学物理 医学物理
- 临床试验 临床试验
背景情况:
- 部放射治疗需要精确的患者固定.
- 传统的封闭式固定化口罩可能会引起患者显著的不适,焦虑和疼痛.
- 优化口罩设计对于改善患者的耐受性和治疗的坚持至关重要.
研究的目的:
- 为了比较患者报告的不适和固定化准确性,在部放射治疗中,开放式面部和封闭式固定化口罩之间.
- 评估口罩设计对患者体验和治疗交付精度的影响.
主要方法:
- 一个单中心,随机的,自我控制的临床试验,涉及30名接受头骨放射治疗的患者.
- 每位患者都接受了开放式面罩和闭合式面罩,治疗计划针对每个患者进行了优化.
- 用视觉模拟尺度 (VAS) 评估患者的不适,焦虑和疼痛.
- 使用kV成像和表面导向放射疗法 (SGRT) 系统测量了分断间和分断内设置变化.
主要成果:
- 与封闭面罩相比,开放面罩导致平均不适度显著降低 (0.5比3.3VAS,P < 0.0001),焦虑和疼痛得分明显降低.
- 封闭的口罩在外轨下部和上部造成了更大的不适.
- 虽然闭口罩显示了较小的间断纵向移动和激光引导的旋转,但SGRT的开口口罩显示了可比的固定精度.
- 在两种口罩类型之间,内断变异性是相似的.
结论:
- 开放式面部固定化口罩在减少头骨放射治疗期间患者的不适方面具有显著的优势.
- 使用开放式面罩不会影响患者定位或固定位置的准确性.
- 开放式面罩代表了骨放射疗法固定化技术的以患者为中心的改进.
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