相关实验视频
Updated: Jun 18, 2026

10:33
Generation of Alginate Microspheres for Biomedical Applications
Published on: August 12, 2012
20.8K
富茶聚糖-冷血改性酸盐微凝的构造,用于益生菌的输送:增强活力和殖民
Rui Sun1, Ying Wang1, Zhongyi Lv1
1College of Food Science and Engineering, Northwest A&F University, YangLing 712100, Shaanxi, China.
International journal of biological macromolecules
|April 27, 2024
概括
这项研究开发了新的微凝,使用富茶多糖和冷血修饰的酸盐纳米-蒙莫里隆尼特来增强益生菌的传递. 微凝显著改善了Lactobacillus kefiranofaciens JKSP109的生存能力和殖民.
科学领域:
- 食品科学与技术 食品科学与技术
- 生物材料工程 生物材料工程
- 微生物学 微生物学
背景情况:
- 益生菌输送系统需要先进的技术来确保微生物的生存能力.
- 富茶多糖化物 (FBTP) 和酸纳米蒙莫里隆石 (AMT) 是有前途的生物材料.
- 冷等离子体修饰为生物材料提供了新的表面功能.
研究的目的:
- 开发和表征微凝,用于增强 Lactobacillus kefiranofaciens JKSP109.9. 的封装和输送.
- 研究冷血治疗和FBTP对微凝特性和益生菌活力的影响.
- 在模拟的胃肠道条件下评估封装益生菌的稳定性和有效性.
主要方法:
- 提取Fu茶多糖 (FBTP) 的方法.
- 酸盐纳米蒙莫里隆尼特 (AMT) 的冷血处理.
- 通过使用C3AMT + FBTP的离子凝制备微凝.
- 封装的 乳酸菌 凯菲拉诺法西恩 JKSP109.9.
- 评估微凝特性 (颗粒大小,形态) 和益生菌活力 (模拟消化,储存).
主要成果:
- 冷等离子处理 (3分钟) 改变了AMT表面电荷;FBTP的添加使颗粒大小减少到223nm.
- C3AMT + FBTP微凝形成了一个密集的结构,其中益生菌分布在多糖网内和纳米颗粒周围.
- 封装的益生菌显示显著更高的生存能力 (8.48日志CFU/g) 和模拟消化后的结肠殖民.
- 在4周的储存期间,FBTP的抗氧化活性保持了益生菌的活力,减少的最小.
结论:
- 开发的C3AMT+FBTP微凝有效地保护乳酸菌kefiranofaciens JKSP109.9.
- 这种新型的输送系统通过模拟胃肠道条件和储存来提高益生菌的生存率.
- 包含FBTP和改造生物材料的益生菌产品显示出作为功能性食品添加剂的潜力.
相关概念视频
Microbial Fermentation
Fermentation is a crucial anaerobic metabolic process that enables microbes to derive energy from sugar without relying on oxygen or an electron transport chain. This process is fundamental to various biological and industrial applications and is classified based on the metabolic products generated.Role of Pyruvate in FermentationPyruvate and its derivatives serve as key electron acceptors in fermentative pathways. The oxidation of NADH to regenerate NAD+ is essential for the continuation of...
Microbes in Food Production
Microbial fermentation is central to food biotechnology, enhancing flavor, texture, preservation, and stability. Fermentative microorganisms metabolize carbohydrates into organic acids, alcohols, and other metabolites that inhibit spoilage organisms and improve digestibility while contributing distinctive sensory qualities.In baking, amylases naturally present in flour hydrolyze starch into monosaccharides such as glucose, which Saccharomyces cerevisiae ferments anaerobically. Through...
Microbes in Beverage Production
Alcoholic beverages such as wine, beer, and spirits are the products of microbial fermentation processes that transform simple sugars into ethanol and a wide array of complex flavor compounds. These transformations rely on the metabolic activities of specific yeasts and bacteria, which are selected and controlled to yield the desired beverage characteristics.Wine Fermentation and MaturationWine production begins with the crushing of grapes to release juice and pulp, forming a must that is...
Microbes in the Production of Fermented Foods
Lactic acid bacteria (LAB) and molds are instrumental in fermenting plant-based foods to enhance preservation and ensure year-round availability. These microbial processes convert plant carbohydrates into organic acids and other metabolites that inhibit spoilage organisms and contribute to the sensory qualities of the final product.In sauerkraut production, cabbage goes through a microbial succession that starts with cocci such as Leuconostoc mesenteroides. These microbes begin fermentation by...
Bioreactor Controls-III
Strain improvement is a foundational strategy in industrial microbiology aimed at maximizing microbial productivity, particularly because natural isolates typically yield commercially valuable products in very low concentrations. Although optimizing the culture medium and environmental conditions can improve yields, these adjustments are inherently limited by the organism’s genetic potential. As a result, the focus shifts toward genetic modifications to enhance biosynthetic capacity. The...
Production of Organic Acids
Lactic acid, an important organic acid extensively applied in food, pharmaceutical, and biodegradable polymer industries, is primarily produced via microbial fermentation. This method is favored over chemical synthesis due to its environmental sustainability and capacity for enantiomerically pure product formation. Among various microbial processes, the fermentation of starch-based substrates stands out due to the abundance and renewability of raw materials like corn and potatoes.Hydrolysis of...

