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增加阻力对在体积控制通风期间由两名临床监测器评估的动态合规性的影响:一个试验肺研究
Daniel Ben-Aderet1, João Hn Soares2, Melissa Lc Bueno2
1William Pritchard Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California Davis, Davis, CA, USA.
Veterinary anaesthesia and analgesia
|April 27, 2024
概括
在机械通风过程中,NM3监测器比E-CAiOV模块更好地区分呼吸系统阻力变化与合规性变化. 这对于在重症监护机构进行精确的呼吸监测至关重要.
科学领域:
- 机械通风机械通风机械通风
- 呼吸系统生理学 呼吸系统生理学
- 医疗器械评估 医疗器械评估
背景情况:
- 在机械通风中,精确评估呼吸机制至关重要.
- 动态符合性 (Cdyn) 是一个关键参数,但其准确性可能会受到呼吸系统阻力增加 (RRS) 的影响.
- 评估不同监测设备在不同呼吸条件下的性能是必不可少的.
研究的目的:
- 在增加呼吸系统阻力 (RRS) 的条件下,比较NM3监测器 (Cdyn(NM3) 和E-CAiOV模块 (Cdyn(ECAiOV) 之间的动态合规 (Cdyn) 测量的准确性.
主要方法:
- 一项前性实验室研究使用了模拟哺乳动物机械通风的训练试验肺 (TTL).
- 模拟包括不同的潮体积 (50和300毫升) 和三个水平的RRS (正常,中度,严重) 与匹配的静态遵守.
- 使用皮尔森和一致性相关系数,布兰德-阿尔特曼图表和通过极地图表的趋势能力来评估协议.
主要成果:
- E-CAiOV模块在所有测试的RRS水平上显示了不可接受的一致性,特别是在严重增加 (R2) 和300毫升的潮体积 (偏差=-54.7%) 时.
- NM3监测器仅在严重的RRS (R2) 与300毫升的潮体积 (偏差=-18.3%) 中显示了不可接受的协议.
- 两种设备都表现出较差的趋势能力,增加了RRS,但在E-CAiOV模块中更为明显.
结论:
- 与E-CAiOV模块相比,NM3监测器在区分呼吸系统阻力变化与呼吸系统合规性变化方面表现出卓越的性能.
- 这些发现凸显了设备选择对于增加呼吸道阻力患者的精确呼吸监测的重要性.
- 需要进一步的临床验证来证实这些结果在不同患者群体.
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